Product description

[Ingredients] This product is a compound preparation, and its components are 0 miconazole nitrate per gram.02 grams, clobetasol propionate 0.5毫克。
【冰球突破mg平台】 This product is a milky cream。
[Appropriate symptoms] For dermatitis, eczema, tinea of the hands and feet, tinea of the stock and allergic dermatitis caused by fungi。
【冰球突破mg平台】 Compound。
[Usage and dosage] External use。Apply evenly to the affected area 1-2 times a day。
[Adverse reactions] Blister, erythema, congestion, burning, pruritus and other irritant symptoms may occur at the site of medication;Folliculitis, skin atrophy and thinning, capillary dilatation;It can also cause dry skin, hirsute, atrophic lines, and increase susceptibility to infection。Long-term large-scale drug use can cause hypercorticosis, showing hypertrichosis, acne, full face, osteoporosis and other symptoms。Occasionally it can cause allergic contact dermatitis。
【冰球突破官方平台】
1.Contraindicated in persons allergic to corticoids and imidazoles。
2.Skin folds such as face, eyes, axils and groin are prohibited。
【冰球突破mg平台】
1.This product contains a corticosteroid preparation for topical use，If long-term, large-scale application or encapsulation therapy，Due to systemic absorption，It can cause reversible suppression of the hypothalamic-pituitary-adrenal (PHA) axis，Some patients may have symptoms such as Cushing syndrome, hyperglycemia and urine sugar,Therefore, this drug can not be used for a long time and a large area，Nor can it be treated with a packet。
2.Any adverse effects that may occur with systemic corticosteroids, including suppression of adrenal function, may occur with topical corticosteroids。Therefore, large-scale use of this product should not exceed 2 weeks;If the drug area only accounts for 5%-10% of the body surface, continuous drug use for 4 weeks。The weekly dosage should not exceed 50g, and systemic adverse reactions are not easy to occur。
3.If irritation or allergic reaction occurs during use, the drug should be stopped and appropriate treatment should be carried out。
4.If accompanied by skin infections, anti-infective drugs must be used。If the symptoms of infection do not improve in time, the drug should be discontinued until the infection is controlled。
5.When the drug character has changed, it is prohibited to use。
【冰球突破mg平台】
1.Pregnant and lactating women should be used under the guidance of a physician after weighing the advantages and disadvantages。
2.Long-term, large-scale use is prohibited for pregnant women。
[Children's medication] For children, such as large-area medication or long-term medication, it will increase the systemic absorption of drugs。It is not suitable for infants and children。
[Elderly drug use] Elderly patients with caution。
[Drug interactions] are unclear。
[Drug overdose] Excessive use of this product can cause systemic adverse reactions of adrenal corticosteroids, resulting in reversible hypothalamic-pituitary-adrenal axis (PHA) inhibition, and some patients may have symptoms such as Cushing syndrome, hyperglycemia and urine sugar。
【冰球突破官方平台】 This product is a compound preparation of miconazole nitrate and clobetasol propionate。Miconazole nitrate is an imidazole anti-bacterial drug，It has bacteriostatic effect，High concentration can also have bactericidal effect;It can inhibit the biosynthesis of sterols such as fungal ergosterol.Acts on fungal cell membranes,Damage fungal cell membrane and change its permeability，Cause the loss of important substances in the cell;It can also inhibit the biosynthesis of triglycerides and phospholipids of fungi.It can also inhibit the activity of oxidation and peroxidase，Causes excessive accumulation of peroxides in the cell，Lead to degeneration and necrosis of fungal subcellular structure;For Candida albicans, it can inhibit the transformation of its spores into aggressive mycelia。
Clobetasol propionate is a highly effective topical corticosteroid with capillary constriction and anti-inflammatory effects。
[Pharmacokinetics] Miconazole nitrate can penetrate the epidermis and enter the stratum corneum of the skin after external use, and remain for several days, with only a small amount of absorption into the whole body;Clobetasol propionate can be absorbed through the intact skin after external use, and is mainly metabolized by the liver and excreted in the urine。
【冰球突破mg平台】 Dark, sealed, stored in a cool place (not more than 20℃)。
【冰球突破官方平台】 Aluminum tube packaging, 15g/piece。
[Effective period] 36 months
[Executive Standard] "Chinese Pharmacopoeia" 2015 edition II
[Approval number] National Medicine approval number H35021395